Article
Sequencing brain metastases and opportunities for targeted therapies.
Pharmacogenomics - 1 Apr 2017
Chukwueke Ugonma N, Brastianos Priscilla K
Abstract excerpt
CNS metastases have long been recognized as a common and late complication of systemic malignancies. They represent the most common tumor of the brain. As outcomes and overall survival improve with better tolerated and more durable responses from therapies for systemic cancers, the incidence and prevalence of brain metastases is likely to increase. Among the most common systemic cancers leading to brain...
Topics
- Antineoplastic Agents
- Biomarkers, Tumor
- Brain Neoplasms
- Humans
- Molecular Targeted Therapy
- Mutation