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Novel combination of CRISPR-based gene drives eliminates resistance and localises spread

2020-08-27

Abstract excerpt

Invasive species are among the major driving forces behind biodiversity loss. Gene drive technology may offer a humane, efficient and cost-effective method of control. For safe and effective deployment it is vital that a gene drive is both self-limiting and can overcome evolutionary resistance. We present HD-ClvR, a novel combination of CRISPR-based gene drives that eliminates resistance and localises spread. As a...

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Identifiers and source

Literature Corpus work
7270e2b8-ac52-587f-ad85-77e47d086a51
DOI
10.1101/2020.08.27.266155
Open publication

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Novel combination of CRISPR-based gene drives eliminates resistance and localises spreadDOI 10.1101/2020.08.27.266155
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