Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Daisy-chain gene drives: The role of low cut-rate, resistance mutations, and maternal deposition.

PLoS genetics - 1 Sept 2022

Verkuijl Sebald A N, Anderson Michelle A E, Alphey Luke, Bonsall Michael B

Abstract excerpt

The introgression of genetic traits through gene drive may serve as a powerful and widely applicable method of biological control. However, for many applications, a self-perpetuating gene drive that can spread beyond the specific target population may be undesirable and preclude use. Daisy-chain gene drives have been proposed as a means of tuning the invasiveness of a gene drive, allowing it to spread efficiently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to CRISPR-Cas Systems
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 36121880
DOI: 10.1371/journal.pgen.1010370
PMCID: PMC9521892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Daisy-chain gene drives: The role of low cut-rate, resistance mutations, and maternal deposition.PMID 36121880Read ↗

Gene Drives Across Engineered Fitness Valleys: Modeling a Design to Prevent Drive SpilloverSemantic proximity Read ↗

Modelling daisy quorum drive: A short-term bridge across engineered fitness valleys.Semantic proximity Read ↗

Rescue by gene swamping as a gene drive deployment strategy.Semantic proximity Read ↗

Can a Population Targeted by a CRISPR-Based Homing Gene Drive Be Rescued?Semantic proximity Read ↗

Current CRISPR gene drive systems are likely to be highly invasive in wild populations.Semantic proximity Read ↗

Designing gene drives to limit spillover to non-target populationsSemantic proximity Read ↗

Designing gene drives to limit spillover to non-target populations.Semantic proximity Read ↗

A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment.Semantic proximity Read ↗

The effect of mating complexity on gene drive dynamicsSemantic proximity Read ↗

Controlling the frequency dynamics of homing gene drives for intermediate outcomes.Semantic proximity Read ↗

Performance characteristics allow for confinement of a CRISPR toxin-antidote gene drive designed for population suppressionSemantic proximity Read ↗

Double drives and private alleles for localised population genetic control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.