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Article

Novel combination of CRISPR-based gene drives eliminates resistance and localises spread.

Scientific reports - 4 Mar 2021

Faber Nicky R, McFarlane Gus R, Gaynor R Chris, Pocrnic Ivan, Whitelaw C Bruce A, Gorjanc Gregor

Abstract excerpt

Invasive species are among the major driving forces behind biodiversity loss. Gene drive technology may offer a humane, efficient and cost-effective method of control. For safe and effective deployment it is vital that a gene drive is both self-limiting and can overcome evolutionary resistance. We present HD-ClvR in this modelling study, a novel combination of CRISPR-based gene drives that eliminates resistance...

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Identifiers

PMID: 33664305
DOI: 10.1038/s41598-021-83239-4
PMCID: PMC7933345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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