Article
Locally Fixed Alleles: A method to localize gene drive to island populations.
Scientific reports - 1 Nov 2019
Sudweeks Jaye, Hollingsworth Brandon, Blondel Dimitri V, Campbell Karl J, Dhole Sumit, Eisemann John D, Edwards Owain, Godwin John, Howald Gregg R, Oh Kevin P, Piaggio Antoinette J, Prowse Thomas A A, Ross Joshua V, Saah J Royden, Shiels Aaron B, Thomas Paul Q, Threadgill David W, Vella Michael R, Gould Fred, Lloyd Alun L
Abstract excerpt
Invasive species pose a major threat to biodiversity on islands. While successes have been achieved using traditional removal methods, such as toxicants aimed at rodents, these approaches have limitations and various off-target effects on island ecosystems. Gene drive technologies designed to eliminate a population provide an alternative approach, but the potential for drive-bearing individuals to escape from the...
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