Article

Antisense oligonucleotides as a targeted therapeutic approach in model of acute myeloid leukemia

2024-10-18

Abstract excerpt

<title>Abstract</title> <p>Background The genetic and epigenetic alterations observed in acute myeloid leukemia (AML) contribute to its heterogeneity, influencing disease progression, response to therapy, and patient outcomes. The use of antisense oligonucleotide (AONs) technology allows the design of oligonucleotide inhibitors based on gene sequence information alone, enabling precise targeting of key molecular...

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Literature Corpus work: 72085b0a-b51b-55f0-99e4-ae18834e5457
DOI: 10.21203/rs.3.rs-5003554/v1

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