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A Highly Sensitive RNA-Based Mutation Detection Approach: Improve the Accuracy and Speed of Liquid Biopsy for Chronic Myeloid Leukemia

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> Background For global molecular diagnostic companies, the occurrence of 1%-10% false positives in detecting single nucleotide variations (SNVs) at the RNA level poses a significant challenge to the application of RNA detection products. In the treatment of chronic myeloid leukemia (CML), highly sensitive and specific rapid detection of <italic>BCR-ABL1</italic> fusion genes and <i...

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Literature Corpus work
e898823e-1d63-5aec-9ac1-0efa6c921888
DOI
10.21203/rs.3.rs-9504218/v1
Open publication

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A Highly Sensitive RNA-Based Mutation Detection Approach: Improve the Accuracy and Speed of Liquid Biopsy for Chronic Myeloid LeukemiaDOI 10.21203/rs.3.rs-9504218/v1
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