Article

NK cells promote cancer immunoediting through tumor-intrinsic loss of interferon-stimulated gene expression

2020-11-23

Abstract excerpt

Natural killer (NK) cells are innate lymphocytes that constantly patrol host tissues against transformed cells in a process known as cancer immunosurveillance. Previous evidence in mice has demonstrated that NK cell-derived IFN-γ can promote immunoevasion by sculpting the immunogenicity of developing tumors in a process known as cancer immunoediting. This process involves the elimination of highly immunogenic “une...

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Literature Corpus work: 71defd8f-5ea2-5b8f-8787-cb50cb989308
DOI: 10.1101/2020.11.23.394353

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