Article
NK-cell Editing Mediates Epithelial-to-Mesenchymal Transition via Phenotypic and Proteomic Changes in Melanoma Cell Lines.
Cancer research - 15 Jul 2018
Huergo-Zapico Leticía, Parodi Monica, Cantoni Claudia, Lavarello Chiara, Fernández-Martínez Juan L, Petretto Andrea, DeAndrés-Galiana Enrique J, Balsamo Mirna, López-Soto Alejandro, Pietra Gabriella, Bugatti Mattia, Munari Enrico, Marconi Marcella, Mingari Maria Cristina, Vermi William, Moretta Lorenzo, González Segundo, Vitale Massimo
Abstract excerpt
Tumor cell plasticity is a major obstacle for the cure of malignancies as it makes tumor cells highly adaptable to microenvironmental changes, enables their phenotype switching among different forms, and favors the generation of prometastatic tumor cell subsets. Phenotype switching toward more aggressive forms involves different functional, phenotypic, and morphologic changes, which are often related to the...
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