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Gene-edited and CAR-NK cells: Opportunities and challenges with engineering of NK cells for immunotherapy

3 Nov 2022

Abstract excerpt

Treatment of many cancers, particularly those that remain difficult to treat or are refractive after standard-of-care therapies, has been challenging with cell-based therapies. Although relatively safe as allogeneic therapies and innately effective against cancers without the need for antigen sensitization, natural killer (NK) cells have necessitated use of genetic manipulation approaches to enhance their...

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PMID: 36420307
DOI: 10.1016/j.omto.2022.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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