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Article

Rapid, point-of-care molecular diagnostics with Cas13

2020-12-16

Abstract excerpt

<h4>Summary</h4> Rapid nucleic acid testing is a critical component of a robust infrastructure for increased disease surveillance. Here, we report a microfluidic platform for point-of-care, CRISPR-based molecular diagnostics. We first developed a nucleic acid test which pairs distinct mechanisms of DNA and RNA amplification optimized for high sensitivity and rapid kinetics, linked to Cas13 detection for specificit...

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Identifiers and source

Literature Corpus work
840769d1-0577-5ee2-a299-e0269bcf34cf
DOI
10.1101/2020.12.14.20247874
Open publication

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Rapid, point-of-care molecular diagnostics with Cas13DOI 10.1101/2020.12.14.20247874
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