Article
Simultaneous identification of viruses and viral variants with programmable DNA nanobait
2021-11-10
Abstract excerpt
Respiratory infections are the major cause of death from infectious disease worldwide. Multiplexed diagnostic approaches are essential as many respiratory viruses have indistinguishable symptoms. We created self-assembled DNA nanobait that can simultaneously identify multiple short RNA targets. The nanobait approach relies on specific target selection via toehold-mediated strand displacement and rapid read-out via...
Topics
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- Advanced biosensing and bioanalysis techniques
- Bacteriophages and microbial interactions
- Biosensors and Analytical Detection
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
Identifiers and source
- Literature Corpus work
- aa224d68-c2ff-5d0d-a386-827ef92986a2
- DOI
- 10.1101/2021.11.05.21265890