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Virus detection via programmable Type III-A CRISPR-Cas systems

27 Sept 2021

Abstract excerpt

Among the currently available virus detection assays, those based on the programmable CRISPR-Cas enzymes have the advantage of rapid reporting and high sensitivity without the requirement of thermocyclers. Type III-A CRISPR-Cas system is a multi-component and multipronged immune effector, activated by viral RNA that previously has not been repurposed for disease detection owing in part to the complex enzyme...

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PMID: 34580296
DOI: 10.1038/s41467-021-25977-7

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