Article

The role of N-terminal acetylation on biomolecular condensation

2025-08-25

Abstract excerpt

N-terminal acetylation (Nt-acetylation) is one of the most prevalent co-translational modifications in eukaryotes, affecting nearly 80% of the human proteome. Despite its ubiquity, the potential impact of this phenomenon on biomolecular condensation has been largely overlooked. Here, we uncover how this chemically subtle modification can exert broad and multifaceted control over phase behaviour, using Grh1, a Golg...

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Literature Corpus work: 25fdc0a4-7030-585a-8577-8377cf043205
DOI: 10.1101/2025.08.21.671499

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