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Regulation of physiological and pathological condensates by molecular chaperones

5 Jan 2025

Abstract excerpt

Biomolecular condensates are dynamic membraneless compartments that regulate a myriad of cellular functions. A particular type of physiological condensate called stress granules (SGs) has gained increasing interest due to its role in the cellular stress response and various diseases. SGs, composed of several hundred RNA-binding proteins, form transiently in response to stress to protect mRNAs from translation and...

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PMID: 39756021
DOI: 10.1111/febs.17390

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