Article

Analyzing and Reconciling Colocalization and Transcriptome-wide Association Studies from the Perspective of Inferential Reproducibility

2021-11-01

Abstract excerpt

Transcriptome-wide association studies and colocalization analysis are popular computational approaches for integrating genetic association data from molecular and complex traits. They show the unique ability to go beyond variant-level genetic association evidence and implicate critical functional units, e.g., genes, in disease etiology. However, in practice, when the two approaches are applied to the same molecul...

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Literature Corpus work: 6f274920-cdd9-5638-95c3-dda412036b69
DOI: 10.1101/2021.10.29.466468

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