Article

DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes

2023-03-24

Abstract excerpt

Most, if not all, proteins are organized in macromolecular assemblies, which represent key functional units regulating and catalyzing the majority of cellular processes in health and disease. Ever-advancing analytical capabilities promise to pinpoint lesions in proteome modularity driving disease phenotypes. Affinity purification of the protein of interest combined with LC-MS/MS (AP-MS) represents the method of ch...

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Literature Corpus work: 82b199b5-9eab-51be-951a-bbbb11c116e2
DOI: 10.1101/2023.03.22.533843

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