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Genetic modulation of immune gene co-expression in the aged mouse hippocampus by the <i>Apbb1ip</i> locus

2025-06-08

Abstract excerpt

Ageing is a major risk factor for many neurodegenerative diseases, and the hippocampus is particularly vulnerable to the effects of ageing. To define the transcriptomic changes related to ageing and the impact of genetic variation, we analysed hippocampal gene expression data generated from a genetically diverse panel of inbred mouse strains belonging to the BXD Family. We applied a combination of differential exp...

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Literature Corpus work
70c687e6-36ee-5a8d-b98b-fafbe78e012f
DOI
10.1101/2025.06.04.657838
Open publication

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Genetic modulation of immune gene co-expression in the aged mouse hippocampus by the <i>Apbb1ip</i> locusDOI 10.1101/2025.06.04.657838
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