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Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues

11 Feb 2021

Abstract excerpt

By combining transcriptomic data with other data sources, inferences can be made about functional changes during ageing. Thus, we conducted a meta-analysis on 127 publicly available microarray and RNA-Seq datasets from mice, rats and humans, identifying a transcriptomic signature of ageing across species and tissues. Analyses on subsets of these datasets produced transcriptomic signatures of ageing for brain,...

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PMID: 33611312
DOI: 10.18632/aging.202648

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