Article

Oncoprotein CoAA repeats interact with RNA polymerase II CTD repeats

2019-06-13

Abstract excerpt

The heptad repeating sequence of the C-terminal domain (CTD) of the largest subunit of RNA polymerase II is highly conserved in eukaryotes. In yeast, a CTD code consisting of pairs of heptad repeats is essential for viability. However, the strict requirement of diheptad repeats for the CTD function in transcription and splicing is unexplained. Here we show that CoAA (gene symbol RBM14), an oncoprotein and mammalia...

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Literature Corpus work: 6fd2794f-1bc0-5d30-893f-ef38436264bb
DOI: 10.1101/671156

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