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Article

The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation.

Molecular biology and evolution - 1 Apr 2008

Liu Pengda, Greenleaf Arno L, Stiller John W

Abstract excerpt

The carboxyl-terminal domain (CTD) of eukaryotic RNA polymerase II is the staging platform for numerous proteins involved in transcription initiation, mRNA processing, and general coordination of nuclear events. Concordant with these central roles in cellular metabolism, the consensus sequence, tandemly repeated structure, and core functions of the CTD are conserved across diverse eukaryotic lineages; however, in...

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PMID: 18209193
DOI: 10.1093/molbev/msn017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation.PMID 18209193Read ↗

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