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Article

The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs.

Human molecular genetics - 15 Apr 2016

Kin Katherine, Chen Xi, Gonzalez-Garay Manuel, Fakhouri Walid D

Abstract excerpt

Non-coding DNA variations play a critical role in increasing the risk for development of common complex diseases, and account for the majority of SNPs highly associated with cancer. However, it remains a challenge to identify etiologic variants and to predict their pathological effects on target gene expression for clinical purposes. Cis-overlapping motifs (COMs) are elements of enhancer regions that impact gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26908612
DOI: 10.1093/hmg/ddw030
PMCID: PMC6281388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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