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Article

The ASCH superfamily: novel domains with a fold related to the PUA domain and a potential role in RNA metabolism.

Bioinformatics (Oxford, England) - 1 Feb 2006

Iyer Lakshminarayan M, Burroughs A Maxwell, Aravind L

Abstract excerpt

Several studies show that transcription coactivators are often bi-functional ribonucleoprotein complexes that also regulate pre-mRNA processing and splicing decisions. Using sensitive sequence profile searches and structural comparisons we show that the C-terminal domain of the human coactivator protein ASC-1 defines a novel superfamily, the ASC-1 homology (ASCH) domain. The approximately 110 amino acid long ASCH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16322048
DOI: 10.1093/bioinformatics/bti767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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