Article

Strain diversity drives heterogeneous responses to tuberculosis combination therapy

2025-10-06

Abstract excerpt

<h4>Background</h4> Strain diversity in Mycobacterium tuberculosis (Mtb) underlies distinct clinical presentations and outcomes, but the range of drug susceptibility phenotypes among clinical isolates is poorly understood. We aimed to identify drug response patterns in phylogenetically diverse clinical isolates to combination treatment. <h4>Methods</h4> Out of 641 drug-sensitive clinical isolates, we selected...

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Literature Corpus work: 6fc51de8-4efc-562b-b44c-0fe1d0c54c3a
DOI: 10.1101/2025.10.06.680645

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