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Article

Strain Diversity and the Evolution of Antibiotic Resistance.

Advances in experimental medicine and biology - 1 Jan 2017

Borrell Sonia, Trauner Andrej

Abstract excerpt

Drug resistance is best thought of as an ongoing biological process. Resistant bacteria must emerge, become established and ultimately transmit in order to be relevant to human health. In this context, genetic diversity can influence the rate and likelihood of resistance emerging; it can also modulate the net physiological impact of resistance and the propensity of an organism to improve any defects that arise...

Topics

Antitubercular Agents
Biological Evolution
Clone Cells
DNA, Bacterial
Drug Resistance, Multiple, Bacterial
Epistasis, Genetic
Genetic Fitness
Genetic Variation
Genome, Bacterial
Humans
Likelihood Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium tuberculosis

Tuberculosis, Multidrug-Resistant

Tuberculosis, Pulmonary

Source

Identifiers

PMID: 29116640
DOI: 10.1007/978-3-319-64371-7_14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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