Article

Transcriptome signature of cell viability predicts drug response and drug interaction for Tuberculosis

2021-02-09

Abstract excerpt

The treatment of tuberculosis (TB), which kills 1.8 million each year, remains difficult, especially with the emergence of multidrug resistant strains of Mycobacterium tuberculosis (Mtb). While there is an urgent need for new drug regimens to treat TB, the process of drug evaluation is slow and inefficient owing to the slow growth rate of the pathogen, the complexity of performing bacteriologic assays in a high-c...

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Literature Corpus work: ffc9ee24-a057-5b50-8887-d7ecdf089339
DOI: 10.1101/2021.02.09.430468

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