Article
Laboratory evolution of Mycobacterium on agar plates for analysis of resistance acquisition and drug sensitivity profiles.
Scientific reports - 23 Jul 2021
Maeda Tomoya, Kawada Masako, Sakata Natsue, Kotani Hazuki, Furusawa Chikara
Abstract excerpt
Drug-resistant tuberculosis (TB) is a growing public health problem. There is an urgent need for information regarding cross-resistance and collateral sensitivity relationships among drugs and the genetic determinants of anti-TB drug resistance for developing strategies to suppress the emergence of drug-resistant pathogens. To identify mutations that confer resistance to anti-TB drugs in Mycobacterium species, we...
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