Article
The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis.
Nature communications - 18 Mar 2023
Waller Natalie J E, Cheung Chen-Yi, Cook Gregory M, McNeil Matthew B
Abstract excerpt
The increasing incidence of drug resistance in Mycobacterium tuberculosis has diminished the efficacy of almost all available antibiotics, complicating efforts to combat the spread of this global health burden. Alongside the development of new drugs, optimised drug combinations are needed to improve treatment success and prevent the further spread of antibiotic resistance. Typically, antibiotic resistance leads...
Topics
- Humans
- Mycobacterium tuberculosis
- Antitubercular Agents
- Drug Resistance, Multiple, Bacterial
- Tuberculosis
- Phenotype
- Microbial Sensitivity Tests
- Tuberculosis, Multidrug-Resistant
