Article

Shared Risk Genes and Casual Relationships across Sex Hormone Related Traits and Alzheimer’s Disease

2026-04-24

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) exhibits marked sex differences. While sex hormone levels across the lifespan likely contribute to this, little remains known about their causal impact and their relation to sex-biased genetic risk for AD. We therefore sought to identify potential shared genetic architectures, as well as causal genes and relationships, between sex hormone-related traits and AD risk. <h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6f223227-8f2f-5df6-a3ac-30ab987c7d68
DOI: 10.64898/2026.04.23.26351626

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Shared Risk Genes and Casual Relationships across Sex Hormone Related Traits and Alzheimer’s DiseaseDOI 10.64898/2026.04.23.26351626Read

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex-disparitiesSemantic proximity Read

Neuropathology-based GWAS for Alzheimer’s disease reveals novel susceptibility loci and highlights sex-specific pathwaysSemantic proximity Read

Integrative Genetic, Proteogenomic, and Multi-omics Analyses Reveal Sex-Biased Causal Genes and Drug Targets in Alzheimer’s DiseaseSemantic proximity Read

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparitiesSemantic proximity Read

An integrated approach to identifying sex-specific genes, transcription factors, and pathways relevant to Alzheimer’s diseaseSemantic proximity Read

Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a vicious cycle.Semantic proximity Read

Sex specific molecular networks and key drivers of Alzheimer’s diseaseSemantic proximity Read

Sex-specific Associations of Gene Expression with Alzheimer’s Disease Neuropathology and Ante-mortem Cognitive PerformanceSemantic proximity Read

An integrated approach to identifying sex-specific genes, transcription factors, and pathways relevant to Alzheimer's diseaseSemantic proximity Read

Sex-specific Associations of Gene Expression with Alzheimer’s Disease Neuropathology and Ante-mortem Cognitive PerformanceSemantic proximity Read

Sex-specific genetic predictors of Alzheimer's disease biomarkers.Semantic proximity Read

Sex-Stratified Transcriptomic Meta-Analysis of Alzheimer’s Disease Reveal Brain Region and Sex Specific DysregulationSemantic proximity Read