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An integrated approach to identifying sex-specific genes, transcription factors, and pathways relevant to Alzheimer's disease

14 Jul 2024

Abstract excerpt

BACKGROUND: Age represents a significant risk factor for the development of Alzheimer's disease (AD); however, recent research has documented an influencing role of sex in several features of AD. Understanding the impact of sex on specific molecular mechanisms associated with AD remains a critical challenge to creating tailored therapeutic interventions. METHODS: The exploration of the sex-based differential...

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PMID: 39009097
DOI: 10.1016/j.nbd.2024.106605

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