Article

Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn’s disease

2023-09-06

Abstract excerpt

We used human full thickness Crohn’s disease (CD) small bowel resection specimens and single cell RNA sequencing to identify potential therapeutic targets for stricturing (S)CD. Using an unbiased approach, 16 cell lineages were assigned within 14,539 sequenced cells from patient-matched SCD and non-stricturing (NSCD) preparations. SCD and NSCD contained identical cell types. Amongst immune cells, B cells and plasm...

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Literature Corpus work: 6f1ff958-9d0d-5edc-bf54-2bc22da7c993
DOI: 10.1101/2023.09.04.556163

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