Article

In vitro and in vivo molecular analysis of cyclooxygenase-2 (COX-2)-dependent and COX-2 independent cytoprotective pathways in the vascular endothelium

2016-01-01

Abstract excerpt

Purpose: Non-steroidal anti-inﬂammatory drugs (NSAIDs) are important for limiting pain and inﬂammation, although many increase the risk of cardiovascular events including myocardial infarction, stroke and heart failure. However, celecoxib (a selective COX-2 inhibitor), has been associated with a more positive cardiovascular proﬁle. We explored the hypothesis that celecoxib induces anti-oxidant and anti-inﬂammatory...

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Literature Corpus work: 6f1045e8-2a72-5a9a-90da-cac3853dd953
DOI: 10.25560/67697

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