Article

A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response

2021-03-31

Abstract excerpt

Alkylating agents damage DNA and proteins and are widely used in cancer chemotherapy. While the cellular responses to alkylation-induced DNA damage have been explored, knowledge of how alkylation damage affects global cellular stress responses is still sparse. Here, we examined the effects of the alkylating agent methylmethane sulfonate (MMS) on gene expression in mouse liver taking advantage of mice deficient in...

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Literature Corpus work: 6e9f4e46-5515-5d76-9e2c-55642fcc6b26
DOI: 10.1101/2021.03.31.437844

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A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein responseDOI 10.1101/2021.03.31.437844Read

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