Article

System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)

2018-09-21

Abstract excerpt

Despite the immense importance of enzyme-substrate reactions, there is a lack of generic and unbiased tools for identifying and prioritizing substrate proteins which are modulated in the structural and functional levels through modification. Here we describe a high-throughput unbiased proteomic method called System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis (SIESTA). The approa...

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Literature Corpus work: 6e829e47-2c59-5c14-b568-68454a9c2670
DOI: 10.1101/423418

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