Article

Machine learning-based exploration of enzyme-substrate networks: SET8-mediated methyllysine and its changing impact within cancer proteomes

2024-02-27

Abstract excerpt

<title>Abstract</title> <p> The exploration of post-translational modifications (PTMs) within the proteome is pivotal for advancing disease and cancer therapeutics. However, identifying genuine PTM sites amid numerous candidates is challenging. Integrating machine learning (ML) models with high-throughput in vitro peptide synthesis has introduced an ML-hybrid search methodology, enhancing enzyme-substrate select...

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Literature Corpus work: fe5e3ea7-4b56-5c42-9f7a-3906e49668d4
DOI: 10.21203/rs.3.rs-3771179/v1

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