Article

Human Endothelial Cells And Fibroblasts Express And Produce The Coagulation Proteins Necessary For Thrombin Generation

2021-08-11

Abstract excerpt

In a previous study, we reported that human endothelial cells (ECs) express and produce their own coagulation factors (F) that can activate cell surface FX without the additions of external proteins or phospholipids. We now describe experiments that detail the expression and production in ECs and fibroblasts of the clotting proteins necessary for formation of active prothrombinase (FV-FX) complexes to produce thro...

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Literature Corpus work: 6e768c17-3217-5e6a-aeb2-329382eb4dcc
DOI: 10.21203/rs.3.rs-784474/v1

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