Article
Thrombin generation in chronic obstructive pulmonary disease: dependence on plasma factor composition.
Thrombosis research - 1 Oct 2011
Undas Anetta, Jankowski Milosz, Kaczmarek Przemysław, Sladek Krzysztof, Brummel-Ziedins Kathleen
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with an increased risk for thromboembolic events. We investigated thrombin generation profiles in COPD patients and their dependence on plasma factor/inhibitor composition. METHODS: Factors (f) (fII, fV, fVII, fVIII, fIX, fX), antithrombin, protein C (PC) and free tissue factor pathway inhibitor (fTFPI) from 60 COPD patients (aged 64.2 ± 10.1...
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