Article

Theoretical Considerations and Empirical Predictions of the Pharmaco- and Population Dynamics of Heteroresistance

2023-09-21

Abstract excerpt

Antibiotics are considered one of the most important contributions to clinical medicine in the last 100 years. Due to the use and overuse of these drugs, there have been increasing frequencies of infections with resistant pathogens. One form of resistance, heteroresistance, is particularly problematic; pathogens appear sensitive to a drug by common susceptibility tests. However, upon exposure to the antibiotic, re...

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Literature Corpus work: 6daaa4ce-bcd3-565f-bc32-3a55dda15031
DOI: 10.1101/2023.09.21.558832

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