Article
Heterogeneity in microbial antibiotic responses: genetic basis and within-host evolution.
Trends in genetics : TIG - 1 Jul 2026
Liu Qingyun, Lyu Liang-Dong
Abstract excerpt
Antibiotic response phenotypes have traditionally been classified as either sensitive or resistant. However, accumulating evidence indicates that bacterial responses to antibiotics are far more heterogeneous than previously appreciated. A growing set of new descriptors-including antibiotic persistence, tolerance, heteroresistance, resilience, and perseverance-has been introduced to capture noncanonical antibiotic...
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