Bacterial heteroresistance mechanisms, dynamics, and emerging diagnostic approaches.

Abstract excerpt

Antibiotic heteroresistance is a form of within-isolate susceptibility heterogeneity in which an apparently susceptible bacterial population contains rare subpopulations capable of growth at substantially higher antibiotic concentrations. It is commonly defined as resistant minorities occurring at frequencies ≥10-7 and growing at concentrations at least eight-fold above those that inhibit the dominant population,...

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• Anti-Bacterial Agents
• Bacteria
• Bacterial Infections
• Drug Resistance, Bacterial
• Microbial Sensitivity Tests