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Article

The population dynamics of antimicrobial chemotherapy.

Antimicrobial agents and chemotherapy - 1 Feb 1997

Lipsitch M, Levin B R

Abstract excerpt

We present and analyze a series of mathematical models for the emergence of resistance during antibiotic treatment of an infected host. The models consider the population dynamics of antibiotic-sensitive and -resistant bacteria during the course of treatment and addresses the following problems: (i) the probability of obtaining a resistant mutant during the course of treatment as a function of antibiotic...

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Source

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Identifiers

PMID: 9021193
DOI: 10.1128/AAC.41.2.363
PMCID: PMC163715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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