Article
CYP2D6 phenotypes and opioid metabolism: the path to personalized analgesia.
Expert opinion on drug metabolism & toxicology - 1 Apr 2022
Ballester Pura, Muriel Javier, Peiró Ana M
Abstract excerpt
INTRODUCTION: Opioids play a fundamental role in chronic pain, especially considering when 1 of 5 Europeans adults, even more in older females, suffer from it. However, half of them do not reach an adequate pain relief. Could pharmacogenomics help to choose the most appropriate analgesic drug? AREAS COVERED: The objective of the present narrative review was to assess the influence of cytochrome P450 2D6 (CYP2D6)...
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