Article

Hippocampal GFAP-positive astrocyte responses to amyloid and tau pathologies

2022-02-28

Abstract excerpt

<h4>Introduction</h4> In Alzheimer’s disease clinical research, glial fibrillary acidic protein (GFAP) released into the cerebrospinal fluid and blood is widely measured and perceived as a biomarker of reactive astrogliosis. However, it was demonstrated that GFAP levels differ in individuals presenting with amyloid-β (Aβ) or tau pathology. The molecular underpinnings behind this specificity are unexplored. Here w...

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Literature Corpus work: 6d07a1bd-fb8c-5417-ad03-e9c02be6d9c9
DOI: 10.1101/2022.02.25.481812

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