Article

Proteomics of the astrocyte secretome reveals changes in their response to soluble oligomeric Aß

2023-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Astrocytes associate with amyloid plaques in Alzheimer’s disease (AD). Astrocytes react to changes in the brain environment, including to increasing concentrations of amyloid-ß (Aß). However, the precise response of astrocytes to soluble small Aß oligomers at concentrations similar to those present in the human brain has not been addressed. In this study, we exposed astrocytes to neuronal media...

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Literature Corpus work: 3b44c19e-28e5-5e50-bb5f-e8d7b56f7115
DOI: 10.1101/2023.01.18.523916

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