Article

High-resolution <i>in vivo</i> identification of miRNA targets by Halo-Enhanced Ago2 Pulldown

2019-10-28

Abstract excerpt

<h4>SUMMARY</h4> The identification of miRNA targets by Ago2 crosslinking-immunoprecipitation (CLIP) methods has provided major insights into the biology of this important class of non-coding RNAs. However, these methods are technically challenging and not easily translated to an in vivo setting. To overcome these limitations and to facilitate the investigation of miRNA functions in mice, we have developed a met...

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Literature Corpus work: 6ce9e55d-54f3-56cc-b9e2-50675d83faa1
DOI: 10.1101/820548

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