Article

Exonuclease assisted mapping of protein-RNA interactions (ePRINT)

2023-05-16

Abstract excerpt

RNA processing is a fundamental mode of gene regulation that is perturbed in a variety of diseases including cancer and neurodegenerative disorders. RNA-binding proteins (RBPs) regulate key aspects of RNA processing including alternative splicing, mRNA degradation and localization by physically binding RNA molecules. Current methods to map these interactions, such as CLIP, rely on purifying single proteins at a ti...

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Literature Corpus work: d410b36d-ee22-55df-9768-1644383a6459
DOI: 10.1101/2023.05.16.540978

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