Article

Integration of spatial transcriptomic and single cell sequencing identifies expression patterns underlying immune and epithelial cell cross-talk in acute kidney injury

2021-01-20

Abstract excerpt

Despite important advances in studying experimental and clinical acute kidney injury (AKI), the pathogenesis of this disease remains incompletely understood. Single cell sequencing studies have closed this knowledge gap by characterizing the transcriptomic signature of different cell types within the kidney. However, the spatial distribution of injury can be regional and affect cells heterogeneously. We first opti...

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Literature Corpus work: 6ce49a32-128f-5ef0-8ca6-3558008cf330
DOI: 10.1101/2021.01.19.427258

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