Article

Transcriptomic responses of the human kidney to acute injury at single cell resolution

2021-12-16

Abstract excerpt

<h4>Background</h4> Acute kidney injury (AKI) occurs frequently in critically ill patients and is associated with adverse outcomes. Cellular mechanisms underlying AKI and kidney cell responses to injury remain incompletely understood. <h4>Methods</h4> We performed single-nuclei transcriptomics, bulk transcriptomics, molecular imaging studies, and conventional histology on kidney tissues from 8 individuals with s...

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Literature Corpus work: fbcc6c61-3c0c-59fc-ac6d-4019b35fd476
DOI: 10.1101/2021.12.15.472619

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