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Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease

2023-11-22

Abstract excerpt

Kidney injury disrupts the intricate renal architecture and triggers limited regeneration, and injury-invoked inflammation and fibrosis. Deciphering molecular pathways and cellular interactions driving these processes is challenging due to the complex renal architecture. Here, we applied single cell spatial transcriptomics to examine ischemia-reperfusion injury in the mouse kidney. Spatial transcriptomics revealed...

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Literature Corpus work
b173d83f-670d-5925-abcd-3e8c60e5545a
DOI
10.1101/2023.11.22.568217
Open publication

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Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and diseaseDOI 10.1101/2023.11.22.568217
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