Article

Single Cell Profiling of Acute Kidney Injury Reveals Novel Transcriptional Signatures, Mixed Identities and Epithelial-to-Stromal Crosstalk

2019-12-30

Abstract excerpt

<h4>Summary</h4> Acute kidney injury (AKI) is a rapid decline of renal function, with an incidence of up to 67% of intensive care unit patients. Current treatments are merely supportive, emphasizing the need for deeper understanding that could lead to improved therapies. We used single cell RNA sequencing, in situ hybridization and protein expression analyses to create comprehensive renal cell specific transcrip...

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Literature Corpus work: ee1e40cc-bfb0-52ea-b632-a8cc3bd94fcb
DOI: 10.1101/2019.12.30.890905

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